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24/08/ · FAP-vaccinated mice also treated with Cyclophosphamide chemotherapy displayed a marked suppression of tumor growth (inhibition ratio =80%) and a prolongation of survival time. In two different models of pulmonary fibrosis, intratracheal bleomycin instillation and thoracic irradiation, the probe finds enlargened mortality and enlargened lung fibrosis in FAP-deficient mice compared with wild-type mice.

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